The Active Mobile Phase Conditioner

The Caloratherm was designed to eliminate band broadening and enhance detector ionization when performing high performance liquid chromatography (HPLC) separations. As the liquid mobile phase enters the column located inside of the column oven, the mobile phase temperature must match the column temperature. The Caloratherm is a small heater that slips over standard 1/16” stainless steal tubing and is controlled independently on the column oven control keypad. The temperature of the mobile phase is detected and the Caloratherm temperature sutomatically adjusts the temperature based on the mobile phase composition.

Caloratherm - The Active Mobile Phase Conditioner

Unique Features of the Caloratherm

  • Dynamic heating that compensates for changing heat capacities
  • Improves chromatographic efficiency and peak shape when used with existing column heaters
  • Can be installed “precolumn” to preheat the mobile phase or “postcolumn” to stabilize the detector
  • Automatically adjusts power input during fast solvent gradients
  • Provides dynamic, independent control of mobile phase temperature
  • Tolerant to flow interruptions
  • Non-invasive to flow path
  • Adds no dead volume
  • Is easy and safe to use

Caloratherm Mobile Phase Conditioner Specifications

Temperature with preheater:

  • 40 ° C to 100 ° C, isothermal

Temperature with Peltier cooling:

  • 0 ° C to 50 ° C, isothermal

Flow rate range:

  • 1.0 to 5.0 mL/min with water, higher with organic mobile phase.

Dimensions (l x h x d):

  • 6.0 x 3.0 x 4.5 inches (15.2 x 7.6 x 11.4 cm)


  • 16 oz (0.454 kg)

Mobile phase:

  • Any HPLC mobile phase

Power requirements:

  • 100-240 VAC, 60 VA

Have questions?

Wondering if we have a solution for your analytical needs? Or ready to get pricing and start today? Get a quote here.

Request a Quote