Supercritical Fluid
Chromatography (SFC)

Series 4000 SFC
Series 4000 SFC Features
Series 4000 SFC Specs
SFC Columns & Accessories

Temperature Programmed HPLC

HPLC Overview
Caloratherm™ Mobile Phase Temp Conditioner
Polaratherm™ Total
   Temperature Controller

Polaratherm™ Specs
Mobile Phase Preheater
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   & Accessories

Selerity Secure-Fit™ Connector

Literature and Brochures

Series 4000 SFC Brochure
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Application Notes
Technical Notes


Main Products Area : SFC 4000

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SFC Brochure

Application Notes

Why use the Series 4000 supercritical fluid chromatograph?

Petroleum, polymer, surfactant, and pharmaceutical industry analysts work with compounds that GC or LC cannot easily separate or detect because of thermal instability, lack of chromophores, and other causes of ineffective separations. The Series 4000 has been designed for use with both nonvolatile and volatile analytes, including thermally labile analytes. It is the new generation of SFC that is rugged, reliable, reproducible and easy to use.

Industry Requirements:

Petroleum Industry
Refineries producing gasoline, diesel, and jet fuels will benefit by using SFC. The ASTM organization has developed and accepted two class fractionation methods using SFC. ASTM D5186 measures the total aromatic and PNA content in diesel and jet fuel, and ASTM D6550 measures the total olefin content in gasoline. These methods are the alternatives to the FIA method ASTM D1319. Some regulatory agencies are requiring the use of ASTM D5186 and D6550 for tighter specs.

Polymer Industry
The Series 4000 provides an easy way to analyze low molecular weight polymers (up to about 5,000 molecular weight), monomers, oligomers, and polymer precursors. Many polymers do not have chromophores sensitive to UV detection; hence the FID on the Selerity Technologies Series 4000 is the most effective detector for these materials.

Nonionic surfactants, found in paints, household chemicals, soaps, beauty care products, and in thousands of other industrial products, are extremely difficult to analyze by GC or LC. Such surfactants are readily analyzed with the Series 4000 using carbon dioxide and the sensitive Series 4000 FID.

The ability to process thermally sensitive compounds coupled with convenience and ease of use make the Series 4000 the first choice for many pharmaceutical applications.

Chemical Industry
Analysts dealing with highly reactive compounds such as isocyanates, achieve reliable and easy analysis by SFC. The operating temperature of SFC means that the analysis of such thermally labile compounds is no problem.

Food Industry
Derivitization is a must when analyzing fatty acids and triglycerides with either GC or LC. The added solvent strength of supercritical carbon dioxide along with the use of an FID makes these analysis quick and easy. The SFC system is fully automated and no derivitization is needed.

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The Series 4000 SFC System is distributed in Central and South America and the Southern United States by Separation Systems, Inc. Click Here to be directed to the Separation Systems Website