Area : HPLC : Caloratherm
specifically for the chromatographer that needs
to increase sample throughput
indicate that separation scientists are finding increasingly more
value in decreased analysis time. The Caloratherm offers that
value by making it possible to perform efficient analyses at temperatures
elevated above ambient. With the use of elevated temperature and
the Caloratherm, it is now possible to increase your flow rates
up to 5 mL/min without losing theoretical
plates and peak symmetry due to the thermal mismatch of your mobile
phase and column temperatures. The Caloratherm is a perfect complement
to all existing column heaters.
Mismatch Could be Robbing You of Theroretical Plates at Temperatures
as Low as 60°C
Chromatogram showing the
effect of preheating the mobile phase as it enters the column. Pink
trace is obtained when the using the Caloratherm. Blue trace is
obtained when the Caloratherm is not used. Eppendorf CH-30 Column
heater at 60°C, Mobile Phase: 20%Acetonitrile:80% 3mM Phosphate
pH 7, Flow rate: 3.0 mL/min, Column: Zorbax SB-C18 150mm x 4.6mm.
Improves Chromatography at Elevated Temperatures
- Increase usable mobile phase temperature range simply by adding
the Caloratherm to your existing system without adding extra dead
- Easily place the heating cartridge within your column heater
between the incoming fluid source and your column.
- Set the Caloratherm control unit anywhere on your bench top
with its small footprint (6.0" x 3.0" x 4.5").
- Improve chromatographic efficiency and peak shape by eliminating
band broadening due to thermal mismatch.
- Decrease run time, increase signal to noise ratios and improve
is versatile - use it to heat or cool the mobile phase
- Utilize dual functionality options by using it in either the
Peltier cooling or active heating mode.
- Provide dynamic, independent temperature control of your mobile
phase immediately before entering the column or post-column for
extended detector stabilization.
uses the Selerity Mobile
Phase Preheater to preheat the mobile phase and eliminate thermal
For technical information,
please see Technical
Notes and Application
Notes. Additional information is also available in the High
Temperature HPLC Brochure.
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